Colon Cancer Alliance for Research and Education for Lynch Syndrome
Our Mission
Educate the public and healthcare professionals about
Lynch Syndrome and to help fund research for a cure for
this disease.
What is Lynch Syndrome?
Lynch Syndrome is a hereditary disorder that affects up
to 1.2 million people in the United States. It increases the
risk of colon, uterine, ovarian, and other cancers. These
cancers often occur at a young age.
Are you at risk?
If multiple family members have cancer and at least one
person is younger than the age of 50, please learn more
about Lynch Syndrome.
CCARE Events and News
Today, March 22, 2025, is Lynch Syndrome Awareness Day.
We are celebrating at the 10th annual LYNKED IN Conference at the Dana-Farber Cancer Institute in Boston.
We are delighted to announce our partnership with the Collaborative Group of the Americas Inherited Gastrointestinal Cancer (CGA-IGC) CCARE Lynch Syndrome is proud to announce the winner of the first CCARE Lynch Syndrome & CGA-IGC Research Award. This is a two-year $36,000 award that invites applications on research, quality improvement, or patient engagement projects that improve the lives of patients and/or their family members with Lynch syndrome. The winners are Dr Holli Loomans-Kropp from Ohio State and Dr. Zachariah Foda from Johns Hopkins. This project will help unify Lynch syndrome research at multiple universities throughout the United States.
Lynch Syndrome Research Studies
Do you have Lynch Syndrome? Click on the link below to learn about an opportunity to participate in a cancer prevention clinical trial. The study is looking at whether we can lower your chance of getting colon cancer and other Lynch cancers by giving you three vaccines, an approach called Tri-Ad5, in combination with an immune-enhancer drug called N-803. Participants may help contribute to the medical advances of tomorrow.
The NIH is sponsoring a Lynch syndrome vaccine trial. This will hopefully lead to reducing the risk of cancer in people with Lynch Syndrome!
Physicians at the Dana-Farber Cancer Institute at Harvard University are creating a registry of Lynch syndrome Patients. Click here for more information.
Looking for Study Participants - Assessing decisions about uterine and ovarian cancer prevention by people with Lynch syndrome
This research survey will allow people with Lynch syndrome to discuss their experiences with uterine and ovarian cancer prevention which may help medical practitioners learn more about decision-making strategies used by the Lynch community to preserve their gynecological health.
Lynch Syndrome Risk Calculator
Researchers at Harvard University developed an on-line Lynch syndrome risk calculator called PREMM. To do a quick calculation based on your family history click the following link.
IGNITE-TX (Identifying individuals for Genetic Testing Treatment for hereditary cancer) is conducting a study to help families share hereditary cancer information with relatives and make decisions about genetic testing. If you or someone in your family has a BRCA1 or BRCA2 mutation or a Lynch syndrome mutation, you may be eligible to participate. Click here for more information.
Lynch Syndrome Family Communication Study
If you are over 18 years old and were recently diagnosed with Lynch syndrome, please consider helping out on improving Family Communication with a research project from the University of Utah Graduate Program in Genetic Counseling and the Huntsman Cancer Institute. It is online, will take 20-30 minutes, and eligible participants may receive a $15 Amazon gift card. If interested, Email Dr. Lingzi Zhong at Lingzi.zhong@hci.utah.edu.
Fundraiser for Mila Goldin by Felix Reznick and Family