Research
Lynch Vaccine Trial:
Do you have Lynch Syndrome? Click on the link to learn about an opportunity to participate in a cancer prevention clinical trial. The study is looking at whether we can lower your chance of getting colon cancer and other Lynch cancers by giving you three vaccines, an approach called Tri-Ad5, in combination with an immune-enhancer drug called N-803. Participants may help contribute to the medical advances of
tomorrow.
The NIH is sponsoring a Lynch syndrome vaccine trial. This will hopefully lead to reducing the risk of cancer in people with Lynch Syndrome!
Study on gynecological health for Lynch Syndrome patients:
This research survey from the Genetic Counseling program at UC Irvine will allow people with Lynch syndrome to discuss their experiences with uterine and ovarian cancer prevention which may help medical practitioners learn more about decision-making strategies used by the Lynch community to preserve their gynecological health.
Family Communication Study
If you are over 18 years old and were recently diagnosed with Lynch syndrome, please consider helping out on improving Family Communication with a research project from the University of Utah Graduate Program in Genetic Counseling and the Huntsman Cancer Institute. It is online, will take 20-30 minutes, and eligible participants may receive a $15 Amazon gift card. If interested, Email Dr. Lingzi Zhong at Lingzi.zhong@hci.utah.edu.
IGNITE-TX (Identifying individuals for Genetic Testing Treatment for hereditary cancer)
IGNITE-TX (Identifying individuals for Genetic Testing Treatment for hereditary cancer) is conducting a study to help families share hereditary cancer information with relatives and make decisions about genetic testing. If you or someone in your family has a BRCA1 or BRCA2 mutation or a Lynch syndrome mutation, you may be eligible to participate. Click here for more information.
Childhood Diagnosis of Lynch Syndrome Study
The University of Maryland School of Medicine Genetic Counseling Program is doing a study on people who were diagnosed with Lynch syndrome before the age of 18 who are interested in sharing their story. Use this link or email kmaloney1@som.umaryland.edu for more information.
Perlman Family CCARE Lynch Syndrome Research Award
Supporting emerging Lynch Syndrome research, the Perlman Family CCARE Lynch Syndrome Research Stipend is presented yearly at the Society of Gynecologic Oncology Annual Meeting on Women’s Cancer.
2024
Alexandria Young, MD, PhD
New York Presbyterian Weill Cornell Medical Center
Project:
One Stop Colon and Endometrial Screening (OnCE): A Prospective Study of Patient Satisfaction with Combined Cancer Screening for Lynch Syndrome.
2023
Alexandria Young, MD, PhD
Mass General Brigham
Project:
The Molecular Features of Lynch-Related Endometrial Cancers
2022
Courtney Riedinger, MD
California State University
Project:
BRCa Negative Breast Tumors as a Potential Source for Identifying MMR Deficiency and Lynch Syndrome
2021
Ryan Kahn, MD
Weill Cornell Medical Center
Project:
CascadeNet: Developing an online site with telephone-based, cascade genetic testing counseling scripts for health-care providers
2020
Rachel Soyoun Kim, MD
University of British Columbia
Project:
Use of next-generation sequencing panel in diagnosis of Lynch syndrome
2019
Theofano Orfanelli, MD
Icahn School of Medicine at Mount Sinai
Project:
Identification of shared immunogenic tumor antigens in patients with gynecologic cancer with microsatellite instability
2018
Shahla Bari, MD
Morehouse School of Medicine
Project:
Effect of HIV and other forms of acquired Immunodeficiency on clinicopathological and treatment outcomes in patients with Lynch syndrome-associated endometrial cancer.
2017
Joseph Dottino, MD, MPH
University of Texas MD Anderson Cancer Center
Project:
Threshold analysis for universal Lynch Syndrome screening
2016
Janelle Pakish, MD
University of Texas MD Anderson Cancer Center
Project:
Immunotherapy and endometrial cancer subtypes: Does the immune microenvironment differ with Lynch syndrome and microsatellite instability
2015
Joshua G. Cohen, MD
UCLA Department of Obstetrics and Gynecology
Project:
Evaluating Progestin Response in Lynch Syndrome Patients Who Desire Conservative Management of Endometrial Hyperplasia/Well-Differentiated Endometrial Carcinoma
2014
Erin E. Greenberg, MD
Women & Infants Hospital of Rhode Island
Project:
Prospective Evaluation of Universal Immunohistochemistry Screening for Diagnosing Lynch Syndrome in Endometrial Cancer Patients in a Large Tertiary Care Center
2013
Miya M. Frick
California State University
Project:
BRCa Negative Breast Tumors as a Potential Source for Identifying MMR Deficiency and Lynch Syndrome